BMI Helps to Calculate the Initial Levothyroxine Dose After Total Thyroidectomy

Abstract After total thyroidectomy, an initial dose of levothyroxine is often prescribed based on the patient’s body weight (1.6 mcg / kg day), regardless mass index (BMI). The current literature required that hormone maintenance therapy (THR) in obese patients differs from non-obese patients. Review clinical processes with papillary carcinoma followed multidisciplinary consultation Endocrine Pathology at CHVNG E a thyroidectomy 2015 to 2017. Patients who achieved euthyroidism THR were included analysis and divided according BMI. Statistical was performed using SPSS version 25.0. A value p <0.05 considered statistically significant. sample 82 patients, 90.2% (n = 74) female 9.8% 8) male, average age 53.02 ± 14.27 years. Of gender, 52.4% 43) menopause. In postoperative period, 14 (17.1%) had normal BMI, 46 (50%) overweight 22 (32.9%) obese. follow-up time 75.3 months (32-128). LT4 achieve BMI categories mentioned above 1.70; 1.54 1.49 kg. higher needed (p <0.05), but lower relation (mcg kg) <0.05). There no differences related need for L-T4 suplementation (p> 0.05). Our study shows de calculation should also take into account Overweight individuals receive than used which goes against what has been described literature. weight-based formula, unlike does not volume distribution well. Other methods, include, example, ideal instead actual weight, are being developed help choose starting dose.